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Glycine is mainly metabolized as follows.
Glycine+Tetrahydrofolic acid+NAD+
↓
CO2+NH3+Methylenetetrahydrofolate+NADH+H+
Tetrahydrofolic acid acts on nucleic acid base composition, amino acid metabolism, etc. as coenzyme of C1 unit transition enzyme. |
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Glycine is source of various bioactive substances.
Glutathione with effect of anti-oxidization and detoxification is peptide of γGlu-Cys-Gly.
Gly, Arg, and Met are converted to creatine which stores energy in the body.
The heme in erythrocyte is biosynthesized from Glycine and succinyl-CoA. |
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